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can you drink alcohol on hydrocodone

Quick answer

No. NIAAA lists hydrocodone (Vicodin) among pain medicines that can interact harmfully with alcohol, with drowsiness, dizziness, increased risk for overdose, slowed or difficult breathing and impaired motor control. Ask your doctor or pharmacist before drinking any alcohol.

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In this article
  1. What NIAAA lists
  2. Timing does not remove the risk
  3. What to do

What NIAAA lists

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) has a table of medicines that interact with alcohol. Under pain medicines it names hydrocodone (Vicodin) and other opioids such as oxycodone (Percocet). The reactions it lists are:

  • Drowsiness and dizziness
  • Increased risk for overdose
  • Slowed or difficult breathing
  • Impaired motor control

Timing does not remove the risk

NIAAA says alcohol and medicines can interact harmfully even if they are not taken at the same time. The table does not cover every medicine or ingredient, so a pharmacist or health care provider should check your exact product, especially combination tablets.

What to do

Read the label and the pharmacy leaflet, and ask your prescriber how long to wait after your last dose. If you have already mixed them and feel very drowsy or have trouble breathing, get emergency help. To count what you drank, see our standard drink calculator.

This is general information, not medical advice. Ask a doctor or pharmacist about your own medicines.

People also ask

Is it safe to drink alcohol with hydrocodone?

NIAAA lists hydrocodone as interacting harmfully with alcohol, including increased risk for overdose and slowed or difficult breathing.

What happens if you mix hydrocodone and alcohol?

NIAAA lists drowsiness, dizziness, increased risk for overdose, slowed or difficult breathing and impaired motor control.

Does spacing out the doses make it safe?

Not necessarily. NIAAA says alcohol and medicines can interact harmfully even if they are not taken at the same time.

General information only, not medical or legal advice. If you have a health condition, take medicines or are pregnant, ask your doctor before drinking alcohol. Never drink and drive.

Sources

  1. NIAAA: Harmful Interactions: Mixing Alcohol with Medicines, read 4 Nov 2026
Written by A to Z Alcohol Editorial Team · Published Jun 12, 2023 · Updated Nov 4, 2026
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