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can you drink alcohol with clonidine

Quick answer

The clonidine tablet label on DailyMed says clonidine may potentiate the CNS-depressive effects of alcohol, barbiturates or other sedating drugs, so alcohol can make drowsiness and dizziness stronger. Ask your doctor or pharmacist before you drink.

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In this article
  1. What the label says
  2. Side effects that stack with alcohol
  3. NIAAA view
  4. What to do

What the label says

The clonidine hydrochloride tablet label (used for high blood pressure) states that clonidine “may potentiate the CNS-depressive effects of alcohol, barbiturates or other sedating drugs.” In plain words, drinking can make the sleepy, slowed feeling stronger.

Side effects that stack with alcohol

  • Drowsiness: about 33 in 100 people.
  • Dizziness: about 16 in 100 people.
  • Fainting (syncope) and palpitations are also listed.
  • “Increased sensitivity to alcohol” is listed among less frequent reactions.

The label also cautions patients about driving or operating machinery because of the sedative effect.

NIAAA view

NIAAA lists Catapres (clonidine) among blood pressure medicines whose combination with alcohol can cause dizziness, fainting and drowsiness.

What to do

Do not drive if you feel dizzy or sleepy, and stand up slowly. The label also lists orthostatic symptoms (dizziness on standing). Ask your doctor or pharmacist about your dose and about extended-release versions, which have their own labels. This is general information, not medical advice.

People also ask

Does alcohol make clonidine stronger?

The label says clonidine may potentiate the CNS-depressive effects of alcohol, meaning more sedation.

How common are drowsiness and dizziness on clonidine?

The label gives about 33 in 100 for drowsiness and 16 in 100 for dizziness.

Is clonidine only for blood pressure?

The tablet label we read lists hypertension. Extended-release versions have separate labels for other uses.

General information only, not medical or legal advice. If you have a health condition, take medicines or are pregnant, ask your doctor before drinking alcohol. Never drink and drive.

Sources

  1. DailyMed (NIH): CLONIDINE HYDROCHLORIDE tablet label, read 4 Nov 2026
  2. NIAAA: Harmful Interactions: Mixing Alcohol with Medicines, read 4 Nov 2026
Written by A to Z Alcohol Editorial Team · Published Jun 10, 2023 · Updated Nov 4, 2026
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