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Medicine & Alcohol

can you drink alcohol with fluconazole 150 mg

Quick answer

The fluconazole label we read (DailyMed) does not say you must avoid alcohol, and it does not list alcohol as an interacting substance. It does warn about liver problems and about dizziness. Ask your pharmacist or doctor before drinking, especially if you have liver disease.

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In this article
  1. What the label says
  2. Why caution still makes sense
  3. General rule for medicines
  4. If you are unsure

What the label says

The fluconazole tablet label on DailyMed gives 150 mg as a single oral dose for vaginal candidiasis. The text we read does not mention alcohol, and its “what should I avoid” section only says not to drive or operate machinery until you know how the tablets affect you.

Why caution still makes sense

  • Liver: the label says fluconazole should be given with caution to people with liver dysfunction, and that serious liver toxicity has occurred, mainly in people with serious underlying conditions. Alcohol also affects the liver.
  • Dizziness: the label says dizziness or seizures may occasionally occur. Alcohol can add to dizziness.

General rule for medicines

NIAAA says alcohol and medicines can interact harmfully even when they are not taken at the same time, and that a pharmacist or health care provider can tell you which medicines interact with alcohol. Its list does not include everything.

If you are unsure

Check your own prescription label, ask the pharmacist, and skip alcohol if you have liver disease or feel dizzy or unwell. We found no official source that sets a waiting time after a single 150 mg dose.

To see what a drink contains, use the standard drink calculator.

People also ask

Is it safe to drink after one 150 mg fluconazole pill?

The label text we read does not forbid alcohol, but we found no official statement that it is safe. Ask your pharmacist or doctor.

Does fluconazole affect the liver?

Yes. The label warns of serious liver toxicity in rare cases and says to use caution in people with liver dysfunction.

Can fluconazole make you dizzy?

The label says dizziness or seizures may occasionally occur, and advises caution when driving or using machines.

General information only, not medical or legal advice. If you have a health condition, take medicines or are pregnant, ask your doctor before drinking alcohol. Never drink and drive.

Sources

  1. U.S. National Library of Medicine DailyMed: Fluconazole tablets label, read 4 Nov 2026
  2. NIAAA: Harmful Interactions: Mixing Alcohol with Medicines, read 4 Nov 2026
  3. MedlinePlus: Fluconazole, read 4 Nov 2026
Written by A to Z Alcohol Editorial Team · Published Jun 11, 2023 · Updated Nov 4, 2026
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