🔍
Medicine & Alcohol

what medications increase blood alcohol level

Quick answer

Some medicines can raise your blood alcohol concentration (BAC) by changing how alcohol is absorbed or broken down. The NIAAA says a medication can influence the absorption and metabolism of alcohol, potentially resulting in higher BACs, and gives the heart and blood pressure medicine verapamil as an example that significantly inhibits alcohol metabolism, leading to prolonged elevated BACs. The interaction can also run the other way: alcohol slows the breakdown of some benzodiazepines.

Free download

Standard Drinks Cheat Sheet (PDF): How many US standard drinks and UK units are in beer, wine, spirits and liqueurs, by can, glass and bottle. 33 rows, each with its source.

We use your email only for this download. No spam. We do not sell it or share it with advertisers. Delete it any time: contact@atozalcohol.com. Privacy policy

Thank you

Your chart is ready

Download the PDF

We use your email only for this download.
In this article
  1. Can medicine raise your blood alcohol level?
  2. Examples the NIAAA names
  3. Who is most at risk
  4. What to do

Can medicine raise your blood alcohol level?

Yes. In its guidance for health professionals, the NIAAA explains that alcohol and medications can interact in several ways, including:

  • Through absorption and metabolism: a medication can influence the absorption and metabolism of alcohol, potentially resulting in higher blood alcohol concentrations (BACs) and other adverse effects.
  • Through metabolism of the medicine: alcohol can speed up or slow down how a medicine is cleared.
  • Through combined effects: alcohol can change what the medicine does in the body, for example adding to drowsiness.

Examples the NIAAA names

  • Verapamil (a calcium channel blocker for blood pressure and heart rhythm): significantly inhibits alcohol metabolism, which leads to prolonged elevated BACs.
  • Some benzodiazepines (such as alprazolam, clonazepam and diazepam, but not lorazepam): here alcohol inhibits the medicine’s metabolism.
  • NSAIDs such as aspirin: combining them with alcohol significantly increases the risk of stomach bleeding (not a BAC effect, but a common danger).

Who is most at risk

The NIAAA says people over 65 are at particularly high risk of harm from alcohol-medication interactions, partly because of age-related changes in how the body responds to both.

What to do

  • Ask your pharmacist whether any of your medicines interact with alcohol; the NIAAA notes its lists are not complete.
  • Never assume you are under a driving limit because of how many drinks you had if you take medicine.

See our guides to common combinations: DayQuil, cough syrup, methocarbamol.

People also ask

What medications increase blood alcohol level?

The NIAAA names verapamil, which significantly inhibits alcohol metabolism and prolongs elevated BACs; other medicines can also affect absorption or metabolism. Ask a pharmacist about yours.

Can medication affect a breathalyzer or BAC?

A medicine can raise your BAC by changing how alcohol is absorbed or broken down (NIAAA), so the same drinks can give a higher level.

Who is most at risk from alcohol-medication interactions?

People over 65, according to the NIAAA.

General information only, not medical or legal advice. If you have a health condition, take medicines or are pregnant, ask your doctor before drinking alcohol. Never drink and drive.

Sources

  1. NIAAA Core Resource on Alcohol: Alcohol-medication interactions, potentially dangerous mixes (revised 05/2025), read 4 Nov 2026
  2. NIAAA: Harmful interactions, mixing alcohol with medicines, read 3 Nov 2026
Written by A to Z Alcohol Editorial Team · Published May 3, 2024 · Updated Nov 4, 2026
About · How we verify this · Editorial policy · Corrections

More in Medicine & Alcohol

All Medicine & Alcohol ›