Can You Safely Drink Alcohol While Taking Fluconazole?
The fluconazole FDA label we read does not mention alcohol, but it warns of rare serious liver toxicity, including deaths, and heavy drinking also stresses the liver. We found no official source giving a safe amount, so ask your doctor or pharmacist before you drink.
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What the label says
The fluconazole tablet label (150 mg, used as a single dose for vaginal yeast infections) does not mention alcohol. It does say fluconazole “has been associated with rare cases of serious hepatic toxicity, including fatalities,” mostly in people with serious underlying conditions, and should be given with caution to people with liver problems.
Side effects of a single 150 mg dose
- Headache: 13%
- Nausea: 7%
- Abdominal pain: 6%
- Diarrhea: 3%
Dizziness was reported by 1%.
Other label warnings
Fluconazole has been linked to QT prolongation (a heart rhythm change), and combining it with erythromycin should be avoided. Stop the drug and seek care if you develop signs of liver disease, such as dark urine or jaundice.
What to do
- Ask your pharmacist whether you should drink at all, especially if you have liver disease or take other medicines.
- If you already drank, watch for nausea, belly pain, dark urine or yellow skin and call a clinician if they appear.
This is general information, not medical advice.
People also ask
Does the fluconazole label ban alcohol?
The label we read does not mention alcohol. It does warn about rare serious liver toxicity.
Can I drink after a single 150 mg fluconazole pill?
We found no official rule. Ask your pharmacist, and watch for side effects such as nausea and abdominal pain.
What are common fluconazole side effects?
For a single 150 mg dose the label lists headache (13%), nausea (7%) and abdominal pain (6%).
Sources
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